Compile Data Set for Download or QSAR
Found 75 of ic50 data for polymerid = 34,343,50001120
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50260153(Apamin | CHEMBL525408 | Octadecapeptide venom)copy SMILEScopy InChI
Affinity DataIC50: 0.0640nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BP1PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50260153(Apamin | CHEMBL525408 | Octadecapeptide venom)copy SMILEScopy InChI
Affinity DataIC50: 0.0640nMAssay Description:Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50260153(Apamin | CHEMBL525408 | Octadecapeptide venom)copy SMILEScopy InChI
Affinity DataIC50: 0.168nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BP1PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50260153(Apamin | CHEMBL525408 | Octadecapeptide venom)copy SMILEScopy InChI
Affinity DataIC50: 0.168nMAssay Description:Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50263327(CHEMBL476339 | N-(4-methylpyridin-2-yl)-4-(pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]apamin from Kca2.3 channel expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BP1PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50264020(CHEMBL489770 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Displacement of [125I]apamin from Kca2.3 channel expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BP1PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50435962(CHEMBL2391655)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of KCa2.3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8FWMPubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50263327(CHEMBL476339 | N-(4-methylpyridin-2-yl)-4-(pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BP1PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50263327(CHEMBL476339 | N-(4-methylpyridin-2-yl)-4-(pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BP1PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50150389(17,23-diazonia-2,9-diazahexacyclo[21.6.2.24,7.210,...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of KCa2.3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8FWMPubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50215069(1,2,3-tris-[3-(4-(N-ethyl)-quinoliniumylamino)-pro...)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of SKca channel-mediated after-hypepolarization in rat sympathetic neuronsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416WSJPubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50215071(CHEMBL375272 | N-[3-(4-quinolinylamino)-propyl]-N-...)copy SMILEScopy InChI
Affinity DataIC50: 93nMAssay Description:Inhibition of SKca channel-mediated after-hypepolarization in rat sympathetic neuronsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416WSJPubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50215076(CHEMBL229982 | N-[3-(4-quinolinylamino)-propyl]-N-...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of SKca channel-mediated after-hypepolarization in rat sympathetic neuronsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416WSJPubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50215070(1,2,3-tri[3-(4-quinolinylamino)-propoxy]-benzene |...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of SKca channel-mediated after-hypepolarization in rat sympathetic neuronsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416WSJPubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50215075(CHEMBL229818 | N-[3-(4-quinolinylamino)-propyl]-3,...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of SKca channel-mediated after-hypepolarization in rat sympathetic neuronsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416WSJPubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50215072(CHEMBL389273 | N-(4-quinolinyl)-3,4-di-[3-(4-quino...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of SKca channel-mediated after-hypepolarization in rat sympathetic neuronsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416WSJPubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50264020(CHEMBL489770 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BP1PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50275960(5-chloro-N-(thiophen-2-ylmethyl)pyrazolo[1,5-a]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50215068(CHEMBL229341 | N-[3-(4-quinolinylamino)-proyl]-3,5...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of SKca channel-mediated after-hypepolarization in rat sympathetic neuronsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416WSJPubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50215073(CHEMBL229340 | N-[3-(4-quinolinyl)-aminopropyl]-N-...)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Inhibition of SKca channel-mediated after-hypepolarization in rat sympathetic neuronsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416WSJPubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50264020(CHEMBL489770 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)copy SMILEScopy InChI
Affinity DataIC50: 543nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BP1PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50275960(5-chloro-N-(thiophen-2-ylmethyl)pyrazolo[1,5-a]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
TargetMethyl-CpG-binding protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM158512(US9034574, XXII)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:DNA binding assays using recombinant MBDs. To produce recombinant His6-tagged MBD polypeptides from human MBD2 (MBD2-MBD), MBD2-MBD cDNA was amplifie...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SSNUS Patent
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50275958((R)-5-chloro-N-(1-phenylethyl)pyrazolo[1,5-a]pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50275792(CHEMBL452406 | N-benzyl-5-chloropyrazolo[1,5-a]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50048403(1,1'-(Deca-4,6-diyne-1,10-diyl)bis(4-amino-2-methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BP1PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50275792(CHEMBL452406 | N-benzyl-5-chloropyrazolo[1,5-a]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50048403(1,1'-(Deca-4,6-diyne-1,10-diyl)bis(4-amino-2-methy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BP1PubMed
TargetMethyl-CpG-binding protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM47368(BDBM77674 | US9034574, XXIV)copy SMILEScopy InChI
Affinity DataIC50: 2.81E+3nMAssay Description:DNA binding assays using recombinant MBDs. To produce recombinant His6-tagged MBD polypeptides from human MBD2 (MBD2-MBD), MBD2-MBD cDNA was amplifie...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SSNUS Patent
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50356161(CHEMBL1909931)copy SMILEScopy InChI
Affinity DataIC50: 2.97E+3nMAssay Description:Inhibition of cloned human SK3 channel expressed in human HEK293 cells by patch clamp assay in the presence of 1 uM intracellular Ca2+More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R211S7PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50377863(AG-525 | CHEMBL257156)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of SK3 expressed in CHO FlipIn cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29XTJPubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50275798(5-chloro-N-(3-chlorobenzyl)pyrazolo[1,5-a]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50377980(CHEMBL558625)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Wistar rat recombinant SK3 channel expressed in HEK293 cells by whole cell patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4QT0PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50275959(5-chloro-N-(1,2-diphenylethyl)pyrazolo[1,5-a]pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50275853(5-chloro-N-(3-nitrobenzyl)pyrazolo[1,5-a]pyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
TargetMethyl-CpG-binding protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM47366(US9034574, XXIII)copy SMILEScopy InChI
Affinity DataIC50: 8.59E+3nMAssay Description:DNA binding assays using recombinant MBDs. To produce recombinant His6-tagged MBD polypeptides from human MBD2 (MBD2-MBD), MBD2-MBD cDNA was amplifie...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SSNUS Patent
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50275797(5-chloro-N-(2-(trifluoromethoxy)benzyl)pyrazolo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
TargetMethyl-CpG-binding protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM50264020(CHEMBL489770 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+4nMAssay Description:DNA binding assays using recombinant MBDs. To produce recombinant His6-tagged MBD polypeptides from human MBD2 (MBD2-MBD), MBD2-MBD cDNA was amplifie...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SSNUS Patent
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50275850(5-chloro-N-(3-methylbenzyl)pyrazolo[1,5-a]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50275852(5-chloro-N-(3-(trifluoromethoxy)benzyl)pyrazolo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50275851(5-chloro-N-(3-(trifluoromethyl)benzyl)pyrazolo[1,5...)copy SMILEScopy InChI
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50275794(5-chloro-N-(2-methylbenzyl)pyrazolo[1,5-a]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50275907(5-chloro-N-(4-(trifluoromethoxy)benzyl)pyrazolo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50275796(5-chloro-N-(2-methoxybenzyl)pyrazolo[1,5-a]pyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
TargetMethyl-CpG-binding protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM158508(US9034574, XVII)copy SMILEScopy InChI
Affinity DataIC50: 1.69E+4nMAssay Description:DNA binding assays using recombinant MBDs. To produce recombinant His6-tagged MBD polypeptides from human MBD2 (MBD2-MBD), MBD2-MBD cDNA was amplifie...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SSNUS Patent
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50215074(CHEMBL425668 | N-(3-guanidinopropyl)-N-[4-(4'-amin...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of SKca channel-mediated after-hypepolarization in rat sympathetic neuronsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416WSJPubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50275793(5-chloro-N-(2-chlorobenzyl)pyrazolo[1,5-a]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50215079(4,4'bis(guanidinomethyl)-cis-stilbene | CHEMBL2291...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of SKca channel-mediated after-hypepolarization in rat sympathetic neuronsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416WSJPubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50215078(CHEMBL373955 | N-(3-guanidinopropyl)-N(8-aminoocty...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of SKca channel-mediated after-hypepolarization in rat sympathetic neuronsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416WSJPubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50275795(5-chloro-N-(2-(trifluoromethyl)benzyl)pyrazolo[1,5...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
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